SCHEMBL9154356

SCHEMBL9154356

C#CCOc1cccc(C(C)=O)c1

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOB P27338 15/20 0.59
MAOA P21397 5/20 0.55
GMPS P49915 1/20 0.54
KMT2A Q03164 2/20 0.53
MEN1 O00255 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.52
MTNR1A P48039 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29241080 0.85 MAOB (0.60) MAOBMAOAKMT2AMEN1SMN1; SMN2
SCHEMBL4398914 0.85 NR4A2 (0.59) MAOBGMPSKMT2A
SCHEMBL30180733 0.85 NR4A2 (0.59) MAOBGMPSKMT2A
SCHEMBL30180651 0.84 MRGPRX4 (0.52) MAOBMAOAGMPSKMT2AMEN1
SCHEMBL1339773 0.84 MRGPRX4 (0.52) MAOBMAOAGMPSKMT2AMEN1
SCHEMBL20704575 0.84 GMPS (0.54) MAOBMAOAGMPSKMT2AMTNR1A
SCHEMBL16789662 0.84 PARP1 (0.56) MAOBMAOAGMPS
SCHEMBL24452584 0.83 CA12 (0.51) MAOBMAOAMTNR1A
SCHEMBL17191014 0.83 MAOB (0.57) MAOBMAOAKMT2AMEN1SMN1; SMN2
SCHEMBL4398931 0.82 TDP1 (0.52) GMPSKMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0443513-B1 Azoxy compounds KOWA CO (JP) 1995-02-22 EP disclosed
US-5264559-A Fungicides KOWA COMPANY LTD. (JP) 1993-11-23 US disclosed
EP-0443513-A2 Azoxy compounds KOWA COMPANY, LTD. (JP) 1991-08-28 EP disclosed