Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154684 | 1.00 | MAOB (0.35) | MAOBMAOARARBGAAMAPT | |
| SCHEMBL9159153 | 0.96 | MAOB (0.36) | MAOBMAOARARBGAAMAPT | |
| SCHEMBL9159159 | 0.96 | MAOB (0.36) | MAOBMAOARARBGAAMAPT | |
| SCHEMBL9766632 | 0.95 | MAOB (0.35) | MAOBMAOARARBGAAMAPT | |
| SCHEMBL9159898 | 0.93 | MAOB (0.38) | MAOBMAOARARBS1PR3RAB9A | |
| SCHEMBL9159903 | 0.93 | MAOB (0.38) | MAOBMAOARARBS1PR3RAB9A | |
| SCHEMBL9158991 | 0.89 | MAOB (0.34) | MAOBMAOAGPR84 | |
| SCHEMBL9158990 | 0.89 | MAOB (0.34) | MAOBMAOAGPR84 | |
| SCHEMBL9244214 | 0.88 | MAOB (0.36) | MAOBMAOARARBGAAMAPT | |
| SCHEMBL9244220 | 0.88 | MAOB (0.36) | MAOBMAOARARBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-B1 | PYRIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1995-03-08 | — | — | EP | disclosed |
| WO-1991004248-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-04 | — | — | WO | disclosed |