Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4813094 | 0.82 | TSHR (0.52) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL7920304 | 0.78 | TSHR (0.48) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL25806 | 0.78 | — | — | |
| SCHEMBL1488043 | 0.78 | TSHR (0.65) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL4808647 | 0.77 | GAA (0.52) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL9138923 | 0.77 | TSHR (0.46) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| Alcohol SCHEMBL11584276 | 0.76 | TSHR (0.56) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| Ethylene SCHEMBL10406317 | 0.75 | — | — | |
| Water SCHEMBL9482345 | 0.75 | — | — | |
| SCHEMBL28956758 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0182523-B1 | Oral hygiene composition and polymers active therein | SMITHKLINE BEECHAM PLC (GB) | 1995-01-11 | — | — | EP | claimed |
| US-5336728-A | Addition-condensation polymers based on an unsaturated acid and polyethers; anticaries and -deposit agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-08-09 | — | — | US | claimed |
| EP-0522668-A2 | Polymers active in oral hygiene compositions | SMITHKLINE BEECHAM PLC (GB) | 1993-01-13 | — | — | EP | claimed |
| US-5079288-A | Antideposit agents for teeth | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-07 | — | — | US | claimed |
| EP-0182523-A2 | Oral hygiene composition and polymers active therein | SMITHKLINE BEECHAM PLC (GB) | 1986-05-28 | — | — | EP | claimed |
| US-5414060-A | Mouthwashes and dentifrices with acrylate polymers modified with ethylene glycol polymers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-05-09 | — | — | US | disclosed |
| EP-0182523-B1 | Oral hygiene composition and polymers active therein | SMITHKLINE BEECHAM PLC (GB) | 1995-01-11 | — | — | EP | disclosed |
| US-5336728-A | Addition-condensation polymers based on an unsaturated acid and polyethers; anticaries and -deposit agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-08-09 | — | — | US | disclosed |
| EP-0522668-A2 | Polymers active in oral hygiene compositions | SMITHKLINE BEECHAM PLC (GB) | 1993-01-13 | — | — | EP | disclosed |
| US-5079288-A | Antideposit agents for teeth | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-07 | — | — | US | disclosed |
| US-5004631-A | Water erodible coating | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-02 | — | — | US | disclosed |
| US-4970269-A | HYDROLYZABLE PAINTS, ANTIFOULING | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-11-13 | — | — | US | disclosed |
| US-4963347-A | ANTICARIES AGENTS; ESTERIFIED AND AMIDATED ACRYLIC ACID POLYMERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-16 | — | — | US | disclosed |
| EP-0232006-A2 | Compositions for surface treatment, polymers therefor, and method of surface treatment | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-08-12 | — | — | EP | disclosed |
| EP-0182523-A2 | Oral hygiene composition and polymers active therein | SMITHKLINE BEECHAM PLC (GB) | 1986-05-28 | — | — | EP | disclosed |