Acrylamide

Acrylamide

SCHEMBL9155318

C=CC(N)=O.O=C(O)C=C(CC(O)O)C(=O)O

nearest known ligand 0.41

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
ALDH1A1 P00352 1/20 0.41
FGFR4 P22455 1/20 0.41
KDM4E B2RXH2 1/20 0.41
GRIK1 P39086 4/20 0.32
GRIK2 Q13002 3/20 0.32
LMNA P02545 1/20 0.32
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
GRIA2 P42262 2/20 0.30
GRIA4 P48058 2/20 0.30
GRIK3 Q13003 2/20 0.30
GRIK5 Q16478 2/20 0.30
GRIA1 P42261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8607102 0.86 KDM4E (0.52) TSHRKDM4EGRIK1GRIK2GRIA2
SCHEMBL5455589 0.86 KDM4E (0.52) TSHRKDM4EGRIK1GRIK2GRIA2
SCHEMBL2855637 0.86 KDM4E (0.52) TSHRKDM4EGRIK1GRIK2GRIA2
SCHEMBL28383512 0.76 KDM4E (0.42) TSHRKDM4ELMNAALOX15HSD17B10
SCHEMBL28770373 0.70 KDM4E (0.41) TSHRKDM4EGRIK1GRIK2LMNA
SCHEMBL11802504 0.70 KDM4E (0.48) TSHRKDM4EGRIK1GRIK2GRIA2
SCHEMBL10937515 0.70 KDM4E (0.48) TSHRKDM4EGRIK1GRIK2GRIA2
SCHEMBL10937503 0.70 KDM4E (0.48) TSHRKDM4EGRIK1GRIK2GRIA2
SCHEMBL10604622 0.69 KDM4E (0.43) TSHRKDM4EGRIK1GRIK2
SCHEMBL28770365 0.69 TSHR (0.39) TSHRALDH1A1KDM4EGRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0530316-B1 CROSS-LINKED CONDUCTIVE POLYMERS AND ANTISTAT LAYERS EMPLOYING THE SAME EASTMAN KODAK CO (US) 1995-01-25 EP disclosed
US-5198499-A CROSS-LINKED POLYMERS FROM VINYL BENZENE SULFONATE SALTS, ETHYLENIC HYDROXY MONOMERS AND HYDROXYL CONTAINING BINDER POLYMERS EASTMAN KODAK COMPANY (US) 1993-03-30 US disclosed
US-5096975-A CROSS-LINKED POLYMERS FROM VINYL BENZENE SULFONATE SALTS AND ETHYLENIC HYDROXY MONOMERS EASTMAN KODAK COMPANY (US) 1992-03-17 US disclosed