Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | RARA | P10276 | 2/20 | 0.48 |
| ▸ | RARG | P13631 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154633 | 1.00 | RARB (0.51) | RARBRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL9154575 | 1.00 | RARB (0.51) | RARBRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL9158950 | 1.00 | RARB (0.51) | RARBRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL9157062 | 1.00 | RARB (0.51) | RARBRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL9153574 | 1.00 | RARB (0.51) | RARBRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL9154201 | 1.00 | RARB (0.51) | RARBRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL9151045 | 1.00 | RARB (0.51) | RARBRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL9153601 | 1.00 | RARB (0.51) | RARBRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL9155674 | 1.00 | RARB (0.51) | RARBRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL9156644 | 1.00 | RARB (0.51) | RARBRAB9ASMN1; SMN2NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252961-B1 | HETEROCYCLIC COMPOUNDS AS COMPONENTS OF LIQUID CRYSTAL PHASES | MERCK PATENT GMBH (DE) | 1995-02-08 | — | — | EP | disclosed |
| US-4913837-A | Heterocyclic compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-04-03 | — | — | US | disclosed |