Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 10/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912401 | 0.81 | RARB (0.53) | TSHRHSD17B10FAAH | |
| SCHEMBL10569888 | 0.80 | TSHR (0.68) | TSHRHSD17B10CYP2A6CYP19A1LOXL2 | |
| SCHEMBL9403378 | 0.79 | TSHR (0.69) | TSHRHSD17B10CYP2A6CYP19A1LOXL2 | |
| SCHEMBL10568033 | 0.78 | HSD17B10 (0.79) | TSHRHSD17B10CYP2A6CYP19A1LOXL2 | |
| SCHEMBL10571506 | 0.78 | CYP2A6 (0.79) | TSHRHSD17B10CYP2A6CYP19A1LOXL2 | |
| SCHEMBL2997975 | 0.78 | HSD17B10 (0.86) | TSHRHSD17B10CYP2A6CYP19A1LOXL2 | |
| SCHEMBL10568237 | 0.78 | HSD17B10 (0.73) | TSHRHSD17B10CYP2A6CYP19A1LOXL2 | |
| SCHEMBL10567414 | 0.78 | HSD17B10 (0.86) | TSHRHSD17B10CYP2A6CYP19A1LOXL2 | |
| SCHEMBL16582463 | 0.78 | TSHR (0.71) | TSHRHSD17B10CYP2A6CYP19A1LOXL2 | |
| SCHEMBL16582531 | 0.78 | TSHR (0.71) | TSHRHSD17B10CYP2A6CYP19A1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424959-B1 | Organosilylalkyl-aromatic compounds | CONSORTIUM ELEKTROCHEM IND (DE) | 1995-02-01 | — | — | EP | disclosed |
| US-5210247-A | ORGANOSILYLALKYLAROMATIC COMPOUNDS | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1993-05-11 | — | — | US | disclosed |
| EP-0424959-A2 | Organosilylalkyl-aromatic compounds | Consortium für elektrochemische Industrie GmbH (DE) | 1991-05-02 | — | — | EP | disclosed |