Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | FURIN | P09958 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9156002 | 1.00 | MEN1 (0.57) | MEN1RAB9AKMT2AGAAF2 | |
| SCHEMBL4157209 | 0.83 | MEN1 (0.57) | MEN1RAB9AKMT2AGAAF2 | |
| SCHEMBL9560101 | 0.83 | MEN1 (0.47) | MEN1RAB9AKMT2AGAAF2 | |
| SCHEMBL30620493 | 0.77 | PARP1 (0.50) | MEN1RAB9AKMT2AMAPTALDH1A1 | |
| SCHEMBL2481256 | 0.77 | F2 (0.55) | MEN1RAB9AKMT2AGAAF2 | |
| SCHEMBL17730485 | 0.77 | F2 (0.55) | MEN1RAB9AKMT2AGAAF2 | |
| SCHEMBL31650872 | 0.77 | F2 (0.55) | MEN1RAB9AKMT2AGAAF2 | |
| SCHEMBL8312824 | 0.77 | F2 (0.55) | MEN1RAB9AKMT2AGAAF2 | |
| SCHEMBL8407427 | 0.77 | PARP1 (0.50) | MEN1RAB9AKMT2AMAPTALDH1A1 | |
| SCHEMBL2804304 | 0.77 | KDM4E (0.58) | RAB9AGAAMAPTALDH1A1FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |