Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154569 | 0.87 | GRM5 (0.47) | ACACBGRM5 | |
| SCHEMBL9158883 | 0.87 | GRM5 (0.47) | ACACBGRM5 | |
| SCHEMBL9156078 | 0.84 | KDM4E (0.50) | ACACBGRM5TSHR | |
| SCHEMBL24687082 | 0.81 | NQO1 (0.54) | NQO1TSHRTDP1 | |
| SCHEMBL31160399 | 0.81 | NQO1 (0.74) | ACACBNQO1TSHRTDP1 | |
| SCHEMBL9153748 | 0.81 | GRM5 (0.50) | ACACBGRM5 | |
| SCHEMBL9496359 | 0.81 | ACACB (0.58) | ACACBGRM5NQO1TSHRTDP1 | |
| SCHEMBL8375667 | 0.80 | NQO1 (0.58) | ACACBNQO1TSHRTDP1 | |
| SCHEMBL9152764 | 0.79 | ACACB (0.50) | ACACBNQO1 | |
| SCHEMBL8774215 | 0.79 | ACACB (0.44) | ACACBNQO1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-B1 | PYRIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1995-03-08 | — | — | EP | disclosed |
| US-5205962-A | Stable liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-27 | — | — | US | disclosed |