Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 17/20 | 0.80 |
| ▸ | CYSLTR1 | Q9Y271 | 17/20 | 0.80 |
| ▸ | PPARG | P37231 | 2/20 | 0.77 |
| ▸ | PPARD | Q03181 | 2/20 | 0.77 |
| ▸ | PPARA | Q07869 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | MAPT | P10636 | 1/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.77 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.77 |
| ▸ | BLM | P54132 | 1/20 | 0.77 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10689725 | 0.89 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL9622384 | 0.88 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL9622277 | 0.88 | CYSLTR2 (0.93) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL29369990 | 0.88 | PPARG (1.00) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL2067483 | 0.88 | PPARG (1.00) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL9192587 | 0.87 | CYSLTR2 (0.63) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL10684678 | 0.87 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL10690096 | 0.87 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL10687758 | 0.87 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL10954268 | 0.87 | PPARG (0.78) | CYSLTR2CYSLTR1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481891-B1 | Phenoxyacetic acid compounds, method for production thereof, and pharmaceutical preparations containing same | TERUMO CORP (JP) | 1995-02-08 | — | — | EP | disclosed |
| EP-0181779-B1 | Heterocyclic compounds, their production, and medicaments containing them | YAMANOUCHI PHARMA CO LTD (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-5258395-A | Slow reacting substance of anaphylaxis antagonists | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1993-11-02 | — | — | US | disclosed |
| US-5179105-A | Antiallergens | TERUMO KABUSHIKI KAISHA (JP) | 1993-01-12 | — | — | US | disclosed |
| US-5177215-A | Heterocyclic compounds and pharmaceutical use thereof | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| EP-0481891-A2 | Phenoxyacetic acid compounds, method for production thereof, and pharmaceutical preparations containing same | TERUMO KABUSHIKI KAISHA (JP) | 1992-04-22 | — | — | EP | disclosed |
| US-4908368-A | SRS-A antagonist | MURASE KIYOSHI (JP) | 1990-03-13 | — | — | US | disclosed |
| US-4855310-A | Thiadiazole compounds as antagonists of SRS-A | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-08-08 | — | — | US | disclosed |
| US-4672066-A | TREATMENT OF ALLERGIC CONDITIONS AND CARDIOVASCULAR DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1987-06-09 | — | — | US | disclosed |
| US-4628115-A | LEUKOTRIENE ANTAGONISTS | HOFFMANN-LA ROCHE INC. (US) | 1986-12-09 | — | — | US | disclosed |
| EP-0181779-A1 | Heterocyclic compounds, their production, and medicaments containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1986-05-21 | — | — | EP | disclosed |