Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 16/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157398 | 1.00 | OPRL1 (0.36) | OPRL1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL9157383 | 1.00 | OPRL1 (0.36) | OPRL1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL9157391 | 1.00 | OPRL1 (0.36) | OPRL1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL9766642 | 0.95 | GAA (0.36) | OPRL1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL9766648 | 0.95 | GAA (0.36) | OPRL1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL9766646 | 0.95 | GAA (0.36) | OPRL1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL9156448 | 0.93 | GAA (0.37) | OPRL1CYP2C9LMNAMAPTMEN1 | |
| SCHEMBL9156440 | 0.93 | GAA (0.37) | OPRL1CYP2C9LMNAMAPTMEN1 | |
| SCHEMBL9156444 | 0.93 | GAA (0.37) | OPRL1CYP2C9LMNAMAPTMEN1 | |
| SCHEMBL9156434 | 0.93 | GAA (0.37) | OPRL1CYP2C9LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-B1 | PYRIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1995-03-08 | — | — | EP | disclosed |
| US-5205962-A | Stable liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-27 | — | — | US | disclosed |
| WO-1991004248-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-04 | — | — | WO | disclosed |