SCHEMBL915860

SCHEMBL915860

CCCCOCCOC[Si](OC)(OC)OC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
CYP3A4 P08684 3/20 0.43
MEN1 O00255 1/20 0.40
THRB P10828 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
MAPT P10636 1/20 0.40
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
HPGD P15428 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
RARB P10826 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LPAR6 P43657 3/20 0.30
LPAR1 Q92633 3/20 0.30
LPAR4 Q99677 3/20 0.30
LPAR5 Q9H1C0 3/20 0.30
LPAR2 Q9HBW0 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29155586 0.95 TSHR (0.42) TSHRCYP3A4MEN1THRBHTT
SCHEMBL8861357 0.88 HTT (0.41) TSHRMEN1THRBHTTKMT2A
SCHEMBL29155575 0.86 HTT (0.45) TSHRMEN1THRBHTTKMT2A
SCHEMBL29155598 0.86 HTT (0.45) TSHRMEN1THRBHTTKMT2A
SCHEMBL29155576 0.86 HTT (0.45) TSHRMEN1THRBHTTKMT2A
SCHEMBL29155594 0.86 HTT (0.45) TSHRMEN1THRBHTTKMT2A
SCHEMBL30727013 0.86 HTT (0.45) TSHRMEN1THRBHTTKMT2A
SCHEMBL30727033 0.86 HTT (0.45) TSHRMEN1THRBHTTKMT2A
SCHEMBL29155583 0.86 HTT (0.45) TSHRMEN1THRBHTTKMT2A
SCHEMBL30726995 0.86 HTT (0.45) TSHRMEN1THRBHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879956-B1 METHOD FOR PRODUCING CROSSLINKABLE ORGANOPOLYSILOXANE DISPERSIONS WACKER CHEMIE AG (DE) 2013-03-06 EP disclosed
EP-2029661-B1 PROCESS FOR THE PRODUCTION OF HIGH-MOLECULAR-WEIGHT ORGANOPOLYSILOXANES WACKER CHEMIE AG (DE) 2011-08-03 EP disclosed
US-7868116-B2 Process for the production of high-molecular-weight organopolysiloxanes WACKER CHEMIE AG (DE) 2011-01-11 US disclosed
US-7582700-B2 Method for the production of emulsions of highly-viscous organopolysiloxanes WACKER CHEMIE AG (DE) 2009-09-01 US disclosed
US-20090198034-A1 PROCESS FOR THE PRODUCTION OF HIGH-MOLECULAR-WEIGHT ORGANOPOLYSILOXANES WACKER CHEMIE AG (DE) 2009-08-06 US disclosed
EP-1721926-B1 Process for the production of dispersions of cross linked organopolysiloxanes WACKER CHEMIE AG (DE) 2009-07-01 EP disclosed
EP-2029661-A1 PROCESS FOR THE PRODUCTION OF HIGH-MOLECULAR-WEIGHT ORGANOPOLYSILOXANES Wacker Chemie AG (DE) 2009-03-04 EP disclosed
EP-1773920-B1 METHOD FOR THE PRODUCTION OF EMULSIONS OF HIGHLY-VISCOUS ORGANOPOLYSILOXANES WACKER CHEMIE AG (DE) 2008-04-09 EP disclosed
US-20080064813-A1 METHOD FOR PRODUCING CROSSLINKABLE ORGANOPOLYSILOXANE DISPERSIONS WACKER CHEMIE AG (DE) 2008-03-13 US disclosed
US-20080033062-A1 Method for the Production of Emulsions of Highly-Viscous Organopolysiloxanes WACKER CHEMIE AG (DE) 2008-02-07 US disclosed
WO-2007147817-A1 PROCESS FOR THE PRODUCTION OF HIGH-MOLECULAR-WEIGHT ORGANOPOLYSILOXANES WACKER CHEMIE AG (DE) 2007-12-27 WO disclosed
EP-1773920-A1 METHOD FOR THE PRODUCTION OF EMULSIONS OF HIGHLY-VISCOUS ORGANOPOLYSILOXANES Wacker Chemie AG (DE) 2007-04-18 EP disclosed
WO-2006119916-A1 METHOD FOR PRODUCING CROSSLINKABLE ORGANOPOLYSILOXANE DISPERSIONS WACKER CHEMIE AG (DE) 2006-11-16 WO disclosed
US-20060258820-A1 Process for preparing dispersions of crosslinked organopolysiloxanes WACKER CHEMIE AG (DE) 2006-11-16 US disclosed
EP-1721926-A1 Process for the production of dispersions of cross linked organopolysiloxanes Wacker Chemie AG (DE) 2006-11-15 EP disclosed
US-7126020-B2 Reactions rapidly complete or proceeds at low temperature such as room temperature; highly viscous and stable products with Si C-bonded radicals containing basic nitrogen WACKER CHEMIE AG (DE) 2006-10-24 US disclosed
EP-1541615-B1 Method for the production of highly viscous organopolysiloxanes WACKER CHEMIE AG (DE) 2006-03-22 EP disclosed
WO-2006015740-A1 METHOD FOR THE PRODUCTION OF EMULSIONS OF HIGHLY-VISCOUS ORGANOPOLYSILOXANES WACKER CHEMIE AG (DE) 2006-02-16 WO disclosed
US-20050131243-A1 Process for preparing highly viscous organopolysiloxanes WACKER-CHEMIE GMBH (DE) 2005-06-16 US disclosed
EP-1541615-A1 Method for the production of highly viscous organopolysiloxanes Wacker-Chemie GmbH (DE) 2005-06-15 EP disclosed