Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 11/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9158671 | 1.00 | GAA (0.38) | GAAMEN1KMT2AMAPK1MAPT | |
| SCHEMBL9158660 | 1.00 | GAA (0.38) | GAAMEN1KMT2AMAPK1MAPT | |
| SCHEMBL9158665 | 1.00 | GAA (0.38) | GAAMEN1KMT2AMAPK1MAPT | |
| SCHEMBL9158611 | 0.96 | GAA (0.40) | GAAMEN1KMT2AMAPK1MAPT | |
| SCHEMBL9158618 | 0.96 | GAA (0.40) | GAAMEN1KMT2AMAPK1MAPT | |
| SCHEMBL9158604 | 0.96 | GAA (0.40) | GAAMEN1KMT2AMAPK1MAPT | |
| SCHEMBL9158601 | 0.96 | GAA (0.40) | GAAMEN1KMT2AMAPK1MAPT | |
| SCHEMBL9154321 | 0.96 | GAA (0.40) | GAAMEN1KMT2AMAPK1MAPT | |
| SCHEMBL9154330 | 0.96 | GAA (0.40) | GAAMEN1KMT2AMAPK1MAPT | |
| SCHEMBL8970349 | 0.92 | CYP2C9 (0.37) | MEN1KMT2AMAPK1MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-B1 | PYRIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1995-03-08 | — | — | EP | disclosed |
| US-5205962-A | Stable liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-27 | — | — | US | disclosed |
| EP-0445248-A1 | PYRIDINE DERIVATIVES. | MERCK PATENT GMBH (DE) | 1991-09-11 | — | — | EP | disclosed |
| WO-1991004248-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-04 | — | — | WO | disclosed |