Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.63 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.59 |
| ▸ | CTSB | P07858 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.59 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.59 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.59 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.59 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | HNF4A | P41235 | 2/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3383712 | 0.85 | IAPP (0.57) | LCKALOX5KDM4EALDH1A1HPGD | |
| SCHEMBL9689519 | 0.83 | LCK (0.71) | LCKKLKB1CTSBMMP9DNMT1 | |
| SCHEMBL10950033 | 0.82 | LCK (0.89) | LCKKLKB1CTSBMMP9DNMT1 | |
| SCHEMBL30790801 | 0.81 | LCK (0.85) | LCKKLKB1CTSBMMP9DNMT1 | |
| SCHEMBL10902984 | 0.77 | KAT8 (0.67) | LCKKLKB1CTSBMMP9DNMT1 | |
| SCHEMBL28761882 | 0.76 | LCK (0.71) | LCKKLKB1CTSBMMP9DNMT1 | |
| SCHEMBL29178595 | 0.76 | LCK (0.77) | LCKKLKB1CTSBMMP9DNMT1 | |
| SCHEMBL2534915 | 0.76 | KAT8 (0.76) | LCKKLKB1CTSBMMP9DNMT1 | |
| SCHEMBL31236856 | 0.76 | LCK (0.71) | LCKKLKB1CTSBMMP9DNMT1 | |
| SCHEMBL28444886 | 0.76 | LCK (0.71) | LCKKLKB1CTSBMMP9DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376460-B1 | Liquid electrophotographic toner | MINNESOTA MINING & MFG (US) | 1995-02-22 | — | — | EP | disclosed |
| EP-0376460-A1 | Liquid electrophotographic toner | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |