Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.65 |
| ▸ | CNR1 | P21554 | 3/20 | 0.57 |
| ▸ | CNR2 | P34972 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | THRA | P10827 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212682 | 1.00 | IDO1 (0.65) | IDO1CNR1CNR2MEN1KMT2A | |
| SCHEMBL7567863 | 1.00 | IDO1 (0.65) | IDO1CNR1CNR2MEN1KMT2A | |
| SCHEMBL30003251 | 1.00 | IDO1 (0.65) | IDO1CNR1CNR2MEN1KMT2A | |
| SCHEMBL23271782 | 1.00 | IDO1 (0.65) | IDO1CNR1CNR2MEN1KMT2A | |
| SCHEMBL2051306 | 1.00 | IDO1 (0.65) | IDO1CNR1CNR2MEN1KMT2A | |
| SCHEMBL23271770 | 1.00 | IDO1 (0.65) | IDO1CNR1CNR2MEN1KMT2A | |
| SCHEMBL11209324 | 1.00 | IDO1 (0.65) | IDO1CNR1CNR2MEN1KMT2A | |
| SCHEMBL8665665 | 0.98 | IDO1 (0.67) | IDO1CNR1CNR2MEN1KMT2A | |
| SCHEMBL30003478 | 0.98 | IDO1 (0.67) | IDO1CNR1CNR2MEN1KMT2A | |
| SCHEMBL2023403 | 0.93 | IDO1 (0.69) | IDO1CNR1CNR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411983-A | Certain hyrdoxy-phosphinyl-oxy-phenylmethyl-imidazolium hydroxide inner salts as PAF antagonists | AMERICAN CYANAMID COMPANY (US) | 1995-05-02 | — | — | US | disclosed |
| US-5234918-A | For cardiovascular, respiratory, carcinogenic and inflammatory disorders | AMERICAN CYANAMID COMPANY (US) | 1993-08-10 | — | — | US | disclosed |
| US-5215975-A | Certain hydroxy-phosphinyl-oxy-phenyl methyl-thiazolium hydroxide inner salts as PAF antagonists | AMERICAN CYANAMID COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| US-5147864-A | Bronchodilator agent, antianaphylactic agent, antishock agent, cardiotonic agent and anticarcinogenic agent | AMERICAN CYANAMID COMPANY (US) | 1992-09-15 | — | — | US | disclosed |
| US-4983592-A | Bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID CO. (US) | 1991-01-08 | — | — | US | disclosed |
| EP-0374513-A2 | Novel bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1990-06-27 | — | — | EP | disclosed |
| US-4897385-A | PHOSPHOCHOLINE DERIVATVES | AMERICAN CYANAMID COMPANY (US) | 1990-01-30 | — | — | US | disclosed |
| EP-0336142-A2 | Novel antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1989-10-11 | — | — | EP | disclosed |
| US-4697031-A | Antihypertensive phosphate derivatives | AMERICAN CYANAMID COMPANY (US) | 1987-09-29 | — | — | US | disclosed |
| US-4460681-A | COLOR FORMING LAYERS, AND SOLVENT SOLUBLE BARRIE LAYERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| US-4419439-A | ALKOXYNAPHTHOL DEVELOPER | FUJI PHOTO FILM CO., LTD. (JP) | 1983-12-06 | — | — | US | disclosed |