Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.40 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15070694 | 1.00 | CASR (0.47) | CASRPLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL13575129 | 1.00 | CASR (0.47) | CASRPLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL9496434 | 1.00 | CASR (0.47) | CASRPLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL9495170 | 1.00 | CASR (0.47) | CASRPLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL16104620 | 1.00 | CASR (0.47) | CASRPLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL30515121 | 1.00 | CASR (0.47) | CASRPLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL10412255 | 0.98 | CASR (0.46) | CASRPLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL17445655 | 0.94 | CASR (0.43) | CASRPLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL9851905 | 0.92 | CASR (0.43) | CASRPLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL25289434 | 0.92 | USP2 (0.50) | CASRPLA2G2APLA2G10PLA2G1BPLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411983-A | Certain hyrdoxy-phosphinyl-oxy-phenylmethyl-imidazolium hydroxide inner salts as PAF antagonists | AMERICAN CYANAMID COMPANY (US) | 1995-05-02 | — | — | US | disclosed |
| US-5234918-A | For cardiovascular, respiratory, carcinogenic and inflammatory disorders | AMERICAN CYANAMID COMPANY (US) | 1993-08-10 | — | — | US | disclosed |
| US-5215975-A | Certain hydroxy-phosphinyl-oxy-phenyl methyl-thiazolium hydroxide inner salts as PAF antagonists | AMERICAN CYANAMID COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| US-5208223-A | Enzyme inhibitors | AMERICAN CYANAMID COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| US-5144045-A | Treatment of inflammatory related disorders | AMERICAN CYANAMID COMPANY (US) | 1992-09-01 | — | — | US | disclosed |
| US-5126291-A | Non-steroidal antiinflammatory agents | AMERICAN CYANAMID COMPANY (US) | 1992-06-30 | — | — | US | disclosed |
| US-4981989-A | Antihypertensive phosphate derivatives and intermediates thereof | AMERICAN CYANAMID COMPANY (US) | 1991-01-01 | — | — | US | disclosed |
| US-4894367-A | CARDIOVASCULAR DISORDERS | AMERICAN CYANAMID COMPANY (US) | 1990-01-16 | — | — | US | disclosed |
| US-4883816-A | SULFONYL DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1989-11-28 | — | — | US | disclosed |
| EP-0336142-A2 | Novel antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1989-10-11 | — | — | EP | disclosed |
| US-4762942-A | AMINO SUBSTITUTED, INNER SALTS | AMERICAN CYANAMID CO. (US) | 1988-08-09 | — | — | US | disclosed |