Fluoride

Fluoride

SCHEMBL9159854

Cc1cccc2ccccc12.F

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 8/20 0.94
ALDH1A1 P00352 5/20 0.94
CYP1A2 P05177 9/20 0.63
HSD17B10 Q99714 5/20 0.61
HPGD P15428 4/20 0.61
TSHR P16473 6/20 0.54
TDP1 Q9NUW8 2/20 0.50
ACHE P22303 1/20 0.47
CYP3A4 P08684 4/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
KEAP1 Q14145 1/20 0.46
HPRT1 P00492 1/20 0.46
CYP2C19 P33261 1/20 0.43
MAPK1 P28482 1/20 0.43
CASP1 P29466 1/20 0.43
RAB9A P51151 1/20 0.43
CASP7 P55210 1/20 0.43
ATM Q13315 1/20 0.43
HIF1A Q16665 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL14954016 0.97 CYP2A6 (0.90) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
Fluoride SCHEMBL14953974 0.97 CYP2A6 (0.90) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
SCHEMBL7517852 0.97 CYP2A6 (1.00) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
SCHEMBL3075 0.97 CYP2A6 (1.00) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
SCHEMBL10684163 0.97 CYP2A6 (1.00) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
SCHEMBL29903166 0.97 CYP2A6 (1.00) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
Hydrochloric Acid SCHEMBL6705962 0.94 CYP2A6 (0.94) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
Water SCHEMBL525370 0.94 CYP2A6 (0.94) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
Ammonia Solution, Strong SCHEMBL7539708 0.94 CYP2A6 (0.94) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD
Ammonia Solution, Strong SCHEMBL21796071 0.94 CYP2A6 (0.94) CYP2A6ALDH1A1CYP1A2HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7086050-A None JP disclosed
JP-H0786050-A GAS-INSULATED ELECTRICAL APPARATUS OSAKA GAS CO LTD 1995-03-31 JP disclosed