Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.55 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9158845 | 1.00 | CYP2C19 (0.71) | CYP2C19KDM4EALDH1A1HTTPKM | |
| Hydrochloric Acid SCHEMBL9426145 | 0.99 | CYP2C19 (0.69) | CYP2C19KDM4EALDH1A1HTTPKM | |
| Hydrochloric Acid SCHEMBL9426011 | 0.99 | CYP2C19 (0.69) | CYP2C19KDM4EALDH1A1HTTPKM | |
| SCHEMBL9425561 | 0.91 | CYP2C19 (0.68) | CYP2C19KDM4EALDH1A1HTTPKM | |
| SCHEMBL10858979 | 0.89 | CYP2C19 (0.69) | CYP2C19KDM4EALDH1A1HTTPKM | |
| SCHEMBL10858976 | 0.89 | CYP2C19 (0.69) | CYP2C19KDM4EALDH1A1HTTPKM | |
| Hydrochloric Acid SCHEMBL10859968 | 0.88 | CYP2C19 (0.67) | CYP2C19KDM4EALDH1A1HTTPKM | |
| Hydrochloric Acid SCHEMBL10859963 | 0.88 | CYP2C19 (0.67) | CYP2C19KDM4EALDH1A1HTTPKM | |
| SCHEMBL9152616 | 0.86 | CYP2C19 (0.62) | CYP2C19KDM4EALDH1A1HTTPKM | |
| SCHEMBL9154894 | 0.85 | CYP2C19 (0.61) | CYP2C19KDM4EALDH1A1HTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533516-B1 | Amides of 1-(alkoxybenzyl)piperazines, processes for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1995-02-08 | — | — | EP | disclosed |
| US-5340809-A | Antihypoxic, antiischemic agents | ADIR ET COMPAGNIE (FR) | 1994-08-23 | — | — | US | disclosed |
| EP-0533516-A2 | Amides of 1-(alkoxybenzyl)piperazines, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-03-24 | — | — | EP | disclosed |