SCHEMBL9160230

SCHEMBL9160230

NCCCC[C@H](N)C(=O)OC(CN=C=O)N=C=O

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.41
RNPEP Q9H4A4 1/20 0.33
CPB2 Q96IY4 2/20 0.33
GNAI3 P08754 1/20 0.32
GNAO1 P09471 1/20 0.32
GNAI1 P63096 1/20 0.32
DPP7 Q9UHL4 10/20 0.31
DPP8 Q6V1X1 5/20 0.31
DPP9 Q86TI2 4/20 0.31
DPP4 P27487 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL331194 0.82 GSR (0.46) GSRRNPEPCPB2GNAI3GNAO1
SCHEMBL331193 0.82 GSR (0.46) GSRRNPEPCPB2GNAI3GNAO1
SCHEMBL132777 0.79 GSR (0.48) GSRRNPEPCPB2GNAI3GNAO1
SCHEMBL132776 0.79 GSR (0.48) GSRRNPEPCPB2GNAI3GNAO1
Lysine SCHEMBL7099410 0.75 GSR (0.59) GSRRNPEP
SCHEMBL28714584 0.75 GSR (0.44) GSRRNPEPCPB2GNAI3GNAO1
SCHEMBL2505103 0.73
SCHEMBL23457451 0.72 GSR (0.57) GSRRNPEPCPB2GNAI3GNAO1
SCHEMBL4204273 0.72 GSR (0.57) GSRRNPEPCPB2GNAI3GNAO1
SCHEMBL1276008 0.72 GSR (0.44) GSRRNPEPCPB2GNAI3GNAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0424836-B1 Preparation process of aliphatic isocyanates MITSUI TOATSU CHEMICALS (JP) 1995-03-15 EP disclosed
US-5136086-A Reacting diamine with gaseous hydrogen chloride and phosgene in ester solvent MITSUI TOATSU CHEMICALS, INC. (JP) 1992-08-04 US disclosed
EP-0424836-A1 Preparation process of aliphatic isocyanates MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-05-02 EP disclosed