Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.67 |
| ▸ | PPARA | Q07869 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005961 | 0.91 | PPARG (0.68) | PPARGPPARA | |
| SCHEMBL7922711 | 0.83 | PPARG (0.80) | PPARGPPARA | |
| SCHEMBL7922721 | 0.83 | PPARG (0.80) | PPARGPPARA | |
| SCHEMBL9083673 | 0.82 | PPARG (0.73) | PPARGPPARA | |
| SCHEMBL9086569 | 0.82 | PPARG (0.84) | PPARGPPARA | |
| SCHEMBL7825579 | 0.82 | PPARG (0.81) | PPARGPPARA | |
| SCHEMBL9085087 | 0.82 | PPARG (0.81) | PPARGPPARA | |
| SCHEMBL7824382 | 0.82 | PPARG (0.77) | PPARGPPARA | |
| SCHEMBL9207919 | 0.82 | PPARG (0.84) | PPARGPPARA | |
| SCHEMBL7826289 | 0.81 | PPARG (0.68) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428048-A | Aryl-N-hydroxyureas as inhibitors of 5-lipoxygenase and anto-arteriosclerotic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-06-27 | — | — | US | disclosed |