Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.91 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9164420 | 1.00 | OXER1 (0.91) | OXER1EGFRMAPTPTGESMEN1 | |
| SCHEMBL9160699 | 1.00 | OXER1 (0.91) | OXER1EGFRMAPTPTGESMEN1 | |
| SCHEMBL9165525 | 1.00 | OXER1 (0.91) | OXER1EGFRMAPTPTGESMEN1 | |
| SCHEMBL286749 | 0.95 | OXER1 (1.00) | OXER1EGFRALDH1A1 | |
| SCHEMBL9267825 | 0.94 | OXER1 (0.84) | OXER1MAPTPTGESMEN1KMT2A | |
| SCHEMBL9166286 | 0.90 | OXER1 (0.74) | OXER1EGFRMAPTMEN1ALDH1A1 | |
| SCHEMBL9265201 | 0.88 | OXER1 (0.74) | OXER1MAPTMEN1ALDH1A1HTT | |
| SCHEMBL9165571 | 0.87 | OXER1 (0.73) | OXER1EGFRMEN1ALDH1A1KMT2A | |
| SCHEMBL9167124 | 0.86 | OXER1 (0.69) | OXER1MAPTALDH1A1 | |
| SCHEMBL9159838 | 0.86 | OXER1 (0.69) | OXER1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648208-A1 | INDOLE DERIVATIVES AS TESTOSTERONE 5 ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994022821-A1 | INDOLE DERIVATIVES AS TESTOSTERONE 5 ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |