Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 8/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.48 |
| ▸ | SELP | P16109 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15809383 | 0.85 | TSHR (0.42) | HMGCRPTPN7TSHR | |
| SCHEMBL8211305 | 0.85 | TSHR (0.42) | HMGCRPTPN7TSHR | |
| SCHEMBL25374210 | 0.85 | TSHR (0.42) | HMGCRPTPN7TSHR | |
| SCHEMBL8371875 | 0.85 | TSHR (0.42) | HMGCRPTPN7TSHR | |
| SCHEMBL5856218 | 0.85 | TSHR (0.42) | HMGCRPTPN7TSHR | |
| SCHEMBL621215 | 0.82 | — | — | |
| SCHEMBL8769477 | 0.82 | — | — | |
| SCHEMBL9744103 | 0.82 | HMGCR (0.64) | HMGCRPTPN7SELPTSHR | |
| SCHEMBL2555532 | 0.82 | HMGCR (0.64) | HMGCRPTPN7SELPTSHR | |
| SCHEMBL5184571 | 0.82 | HMGCR (0.64) | HMGCRPTPN7SELPTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5442065-A | Antitumor agents | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1995-08-15 | — | — | US | disclosed |