Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9167292 | 0.82 | CYP19A1 (0.44) | CYP19A1MAOB | |
| SCHEMBL9167053 | 0.81 | CYP19A1 (0.46) | CYP19A1MAOB | |
| SCHEMBL9167962 | 0.81 | CYP19A1 (0.45) | CYP19A1KDM4EL3MBTL1 | |
| SCHEMBL9158128 | 0.81 | CYP19A1 (0.45) | CYP19A1MAOBEPHX2 | |
| SCHEMBL1507799 | 0.80 | CYP19A1 (0.46) | CYP19A1 | |
| SCHEMBL8408994 | 0.79 | CYP19A1 (0.45) | CYP19A1EPHX2PTGDR2 | |
| SCHEMBL9160207 | 0.77 | CYP19A1 (0.37) | CYP19A1KDM5B | |
| SCHEMBL13813062 | 0.77 | CA12 (0.46) | CYP19A1MAOBEPHX2KDM4EGAA | |
| SCHEMBL8410909 | 0.77 | CYP19A1 (0.54) | CYP19A1EPHX2 | |
| SCHEMBL9165088 | 0.77 | CA12 (0.47) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5473078-A | Aromatase inhibiting compounds | CIBA-GEIGY CORPORATION (US) | 1995-12-05 | — | — | US | disclosed |
| US-5352795-A | Condensing triazolylmethylbenzonitrile with fluorobenzonitrile under basic conditions using alkali metal alkoxide | CIBA-GEIGY CORPORATION (US) | 1994-10-04 | — | — | US | disclosed |
| US-5112845-A | Inhibitors of estrogen synthesis, veterinary medicine | CIBA-GEIGY CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |
| US-4978672-A | Alpha-heterocyclc substituted tolunitriles | CIBA-GEIGY CORPORATION (US) | 1990-12-18 | — | — | US | disclosed |