⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5431872 | 0.78 | TDP1 (0.32) | — | |
| SCHEMBL9163997 | 0.76 | BACE1 (0.30) | — | |
| SCHEMBL9368819 | 0.75 | — | — | |
| SCHEMBL2675755 | 0.75 | — | — | |
| SCHEMBL7748956 | 0.73 | — | — | |
| SCHEMBL6470838 | 0.73 | — | — | |
| SCHEMBL10583330 | 0.71 | — | — | |
| SCHEMBL10012988 | 0.71 | TSHR (0.48) | — | |
| SCHEMBL2572442 | 0.71 | — | — | |
| SCHEMBL9312673 | 0.71 | TDP1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215654-B1 | Macrolide antibiotics and their preparation | AMERICAN CYANAMID CO (US) | 1995-03-15 | — | — | EP | disclosed |
| EP-0307224-B1 | Macrolide compounds | AMERICAN CYANAMID CO (US) | 1994-08-24 | — | — | EP | disclosed |
| EP-0307225-B1 | Macrolide compounds | AMERICAN CYANAMID CO (US) | 1994-08-24 | — | — | EP | disclosed |
| US-5336789-A | Also insecticides, miticides, nematocides | AMERICAN CYANAMID COMPANY (US) | 1994-08-09 | — | — | US | disclosed |
| EP-0238258-B1 | Macrolide compounds | AMERICAN CYANAMID CO (US) | 1994-01-26 | — | — | EP | disclosed |
| EP-0237341-B1 | MACROLIDE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1993-09-22 | — | — | EP | disclosed |
| US-5192777-A | Antibiotics | AMERICAN CYANAMID COMPANY (US) | 1993-03-09 | — | — | US | disclosed |
| US-5185456-A | Insecticides, nematocids, miticides; antibiotics | AMERICAN CYANAMID COMPANY (US) | 1993-02-09 | — | — | US | disclosed |
| EP-0241146-B1 | MACROLIDE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1993-02-03 | — | — | EP | disclosed |
| EP-0231104-B1 | MACROLIDE ANTIBIOTICS AND THEIR PREPARATION | AMERICAN CYANAMID COMPANY (US) | 1992-09-09 | — | — | EP | disclosed |
| US-4900753-A | PESTICIDES | AMERICAN CYANAMID COMPANY (US) | 1990-02-13 | — | — | US | disclosed |
| EP-0327270-A2 | Macrolide compounds | AMERICAN CYANAMID COMPANY (US) | 1989-08-09 | — | — | EP | disclosed |
| EP-0307225-A2 | Macrolide compounds | AMERICAN CYANAMID COMPANY (US) | 1989-03-15 | — | — | EP | disclosed |
| EP-0307224-A2 | Macrolide compounds | AMERICAN CYANAMID COMPANY (US) | 1989-03-15 | — | — | EP | disclosed |
| EP-0241146-A1 | Macrolide compounds | AMERICAN CYANAMID COMPANY (US) | 1987-10-14 | — | — | EP | disclosed |
| EP-0238259-A1 | Macrolide compounds | AMERICAN CYANAMID COMPANY (US) | 1987-09-23 | — | — | EP | disclosed |
| EP-0238258-A1 | Macrolide compounds | AMERICAN CYANAMID COMPANY (US) | 1987-09-23 | — | — | EP | disclosed |
| EP-0237341-A1 | Macrolide compounds | AMERICAN CYANAMID COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |
| EP-0231104-A1 | Macrolide antibiotics and their preparation | AMERICAN CYANAMID COMPANY (US) | 1987-08-05 | — | — | EP | disclosed |
| EP-0215654-A2 | Macrolide antibiotics and their preparation | AMERICAN CYANAMID COMPANY (US) | 1987-03-25 | — | — | EP | disclosed |