Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 12/20 | 0.46 |
| ▸ | PPARD | Q03181 | 8/20 | 0.45 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9163381 | 0.92 | HPGD (0.53) | NPC1HPGDTSHRRAB9ASMN1; SMN2 | |
| SCHEMBL9158453 | 0.90 | PPARA (0.59) | NPC1HPGDTSHRRAB9ASMN1; SMN2 | |
| SCHEMBL9165782 | 0.89 | PPARA (0.50) | NPC1HPGDTSHRRAB9ASMN1; SMN2 | |
| SCHEMBL9162214 | 0.89 | NPC1 (0.50) | NPC1HPGDTSHRRAB9ASMN1; SMN2 | |
| SCHEMBL9162147 | 0.87 | PPARA (0.48) | NPC1HPGDTSHRRAB9ASMN1; SMN2 | |
| SCHEMBL9165311 | 0.87 | PPARA (0.52) | NPC1HPGDTSHRRAB9ASMN1; SMN2 | |
| SCHEMBL9156745 | 0.85 | TSHR (0.48) | NPC1HPGDTSHRRAB9ASMN1; SMN2 | |
| SCHEMBL9163276 | 0.83 | PPARA (0.48) | PPARAPPARDPPARG | |
| SCHEMBL9163552 | 0.81 | PPARA (0.48) | PPARAPPARDPPARG | |
| SCHEMBL10878193 | 0.80 | PPARA (0.45) | NPC1RAB9ASMN1; SMN2ATMPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460472-B1 | Carbamic acid derivatives, their production and use | SUMITOMO CHEMICAL CO (JP) | 1995-03-08 | — | — | EP | claimed |