Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9159838 | 1.00 | OXER1 (0.69) | OXER1SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9166224 | 1.00 | OXER1 (0.69) | OXER1SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9169764 | 1.00 | OXER1 (0.69) | OXER1SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9167124 | 1.00 | OXER1 (0.69) | OXER1SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9166603 | 1.00 | OXER1 (0.69) | OXER1SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9161654 | 1.00 | OXER1 (0.69) | OXER1SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9162572 | 0.91 | OXER1 (0.58) | OXER1SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9166418 | 0.91 | OXER1 (0.57) | OXER1SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9164420 | 0.86 | OXER1 (0.91) | OXER1MAPTALDH1A1 | |
| SCHEMBL9160699 | 0.86 | OXER1 (0.91) | OXER1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648208-A1 | INDOLE DERIVATIVES AS TESTOSTERONE 5 ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994022821-A1 | INDOLE DERIVATIVES AS TESTOSTERONE 5 ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |