Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.48 |
| ▸ | ACHE | P22303 | 8/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9170775 | 0.94 | EPHX1 (0.54) | EPHX1NAAACASP2MEN1KMT2A | |
| SCHEMBL9166245 | 0.92 | EPHX1 (0.57) | EPHX1NAAACASP2 | |
| SCHEMBL9167760 | 0.92 | EPHX1 (0.57) | EPHX1NAAACASP2 | |
| SCHEMBL9172408 | 0.92 | EPHX1 (0.57) | EPHX1NAAACASP2 | |
| SCHEMBL9163796 | 0.92 | EPHX1 (0.57) | EPHX1NAAACASP2 | |
| SCHEMBL9171880 | 0.92 | EPHX1 (0.57) | EPHX1NAAACASP2 | |
| SCHEMBL9169116 | 0.92 | EPHX1 (0.57) | EPHX1NAAACASP2 | |
| SCHEMBL9172390 | 0.92 | EPHX1 (0.57) | EPHX1NAAACASP2 | |
| SCHEMBL9172022 | 0.92 | EPHX1 (0.57) | EPHX1NAAACASP2 | |
| SCHEMBL9171562 | 0.92 | EPHX1 (0.57) | EPHX1NAAACASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519427-B1 | N-substituted-3-iodopropiolamide, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-04-26 | — | — | EP | claimed |
| EP-0552418-A1 | N-substituted-3-iodopropiolamide, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-07-28 | — | — | EP | claimed |
| EP-0519427-A2 | N-substituted-3-iodopropiolamide, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-23 | — | — | EP | claimed |
| JP-5255215-A | — | — | None | — | — | JP | disclosed |
| EP-0519427-B1 | N-substituted-3-iodopropiolamide, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-04-26 | — | — | EP | disclosed |
| JP-H05255215-A | N-SUBSTITUTED-3-IODOPROPIOLIC ACID AMIDE COMPOUND, ITS PRODUCTION AND USE | TAKEDA CHEM IND LTD | 1993-10-05 | — | — | JP | disclosed |
| EP-0552418-A1 | N-substituted-3-iodopropiolamide, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |
| EP-0519427-A2 | N-substituted-3-iodopropiolamide, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-23 | — | — | EP | disclosed |