Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPYD | Q12882 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9163739 | 0.88 | DPYD (0.65) | DPYD | |
| SCHEMBL11448290 | 0.85 | PNP (0.54) | DPYD | |
| SCHEMBL1752654 | 0.80 | DPYD (0.65) | DPYD | |
| SCHEMBL9090379 | 0.78 | DPYD (0.70) | DPYD | |
| SCHEMBL30241946 | 0.78 | DPYD (0.56) | DPYD | |
| SCHEMBL31223167 | 0.77 | DPYD (0.77) | DPYD | |
| SCHEMBL9172009 | 0.77 | DPYD (0.77) | DPYD | |
| SCHEMBL2672649 | 0.77 | TYMP (0.71) | — | |
| SCHEMBL30368346 | 0.75 | DPYD (1.00) | DPYD | |
| SCHEMBL11456150 | 0.75 | DPYD (0.61) | DPYD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649413-A1 | URACIL DERIVATIVES AS ENZYME INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-04-26 | — | — | EP | disclosed |
| WO-1994001414-A1 | URACIL DERIVATIVES AS ENZYME INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-01-20 | — | — | WO | disclosed |