Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9167173 | 0.91 | OXER1 (0.66) | OXER1FFAR1MAPTRXFP1EGFR | |
| SCHEMBL9168348 | 0.88 | OXER1 (0.50) | OXER1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9165563 | 0.86 | OXER1 (0.48) | OXER1MAPTMTNR1AMTNR1BMEN1 | |
| SCHEMBL9166060 | 0.85 | OXER1 (0.47) | OXER1FFAR1MAPTRXFP1EGFR | |
| SCHEMBL9166856 | 0.81 | OXER1 (0.53) | OXER1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9160593 | 0.79 | OXER1 (0.61) | OXER1MAPTEGFRMTNR1AMTNR1B | |
| SCHEMBL9165482 | 0.79 | OXER1 (0.63) | OXER1MAPTEGFRMTNR1AMTNR1B | |
| SCHEMBL9169003 | 0.79 | OXER1 (0.67) | OXER1MAPTEGFRMTNR1AMTNR1B | |
| SCHEMBL286749 | 0.77 | OXER1 (1.00) | OXER1EGFRHPGDKDM4EALDH1A1 | |
| SCHEMBL9164420 | 0.77 | OXER1 (0.91) | OXER1MAPTEGFRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648208-A1 | INDOLE DERIVATIVES AS TESTOSTERONE 5 ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994022821-A1 | INDOLE DERIVATIVES AS TESTOSTERONE 5 ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |