Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE6D | O43924 | 3/20 | 0.62 |
| ▸ | HMGCR | P04035 | 5/20 | 0.61 |
| ▸ | SLCO1B1 | Q9Y6L6 | 4/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.61 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | RHOC | P08134 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.48 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14694095 | 0.91 | SLCO1B1 (0.67) | PDE6DHMGCRSLCO1B1ABCB1ABCC2 | |
| SCHEMBL8798106 | 0.90 | SLCO1B1 (0.65) | PDE6DHMGCRSLCO1B1ABCB1ABCC2 | |
| SCHEMBL8798107 | 0.90 | SLCO1B1 (0.65) | PDE6DHMGCRSLCO1B1ABCB1ABCC2 | |
| SCHEMBL12665705 | 0.89 | SLCO1B1 (0.67) | PDE6DHMGCRSLCO1B1ABCB1ABCC2 | |
| SCHEMBL917330 | 0.88 | SLCO1B1 (0.62) | PDE6DHMGCRSLCO1B1ABCB1ABCC2 | |
| SCHEMBL916077 | 0.88 | SLCO1B1 (0.62) | PDE6DHMGCRSLCO1B1ABCB1ABCC2 | |
| SCHEMBL916342 | 0.88 | SLCO1B1 (0.64) | PDE6DHMGCRSLCO1B1ABCB1ABCC2 | |
| SCHEMBL14694053 | 0.88 | SLCO1B1 (0.62) | PDE6DHMGCRSLCO1B1ABCB1ABCC2 | |
| SCHEMBL916569 | 0.87 | SLCO1B1 (0.61) | PDE6DHMGCRSLCO1B1ABCB1ABCC2 | |
| SCHEMBL14163369 | 0.87 | SLCO1B1 (0.64) | PDE6DHMGCRSLCO1B1ABCB1ABCC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245008-B1 | METHOD FOR THE PREPARATION OF ATORVASTATIN AND INTERMEDIATES USED THEREIN | CHONG KUN DANG PHARM CORP (KR) | 2013-02-20 | — | — | EP | disclosed |
| US-8178697-B2 | Method for the preparation of atorvastatin and intermediates used therein | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2012-05-15 | — | — | US | disclosed |
| US-20110015407-A1 | METHOD FOR THE PREPARATION OF ATORVASTATIN AND INTERMEDIATES USED THEREIN | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015407-A1 | METHOD FOR THE PREPARATION OF ATORVASTATIN AND INTERMEDIATES USED THEREIN | HMGCR, PCSK9, CETP | PDE6D 1619/4885HMGCR 1/4885SLCO1B1 425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.