Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 6/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.47 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28579538 | 0.78 | MEN1 (0.55) | TYMSBCHEACHEHRH4GSR | |
| SCHEMBL29483383 | 0.78 | MEN1 (0.55) | TYMSBCHEACHEHRH4GSR | |
| SCHEMBL9167306 | 0.77 | TYMS (0.57) | TYMSACHEKDM4EALDH1A1 | |
| SCHEMBL6648263 | 0.76 | TYMS (1.00) | TYMS | |
| SCHEMBL29624015 | 0.72 | TYMS (0.58) | TYMSHRH4XDH | |
| SCHEMBL4877642 | 0.72 | BCHE (0.57) | BCHEACHEDYRK1AHRH4KDM4E | |
| SCHEMBL31322343 | 0.72 | MAPK1 (0.51) | TYMSBCHEACHEDYRK1AGSR | |
| SCHEMBL7049426 | 0.71 | BCHE (0.65) | BCHEACHEDYRK1AHRH4KDM4E | |
| Hydrochloric Acid SCHEMBL8059101 | 0.70 | BCHE (0.63) | BCHEACHEDYRK1AHRH4KDM4E | |
| SCHEMBL4588982 | 0.69 | HRH4 (0.57) | BCHEACHEDYRK1AHRH4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123750-B1 | Condensed amino pyrimidinones and their use in the treatment and prophylaxis of viral infections | BIOMEASURE INC (US) | 1995-04-26 | — | — | EP | claimed |