SCHEMBL9167239

SCHEMBL9167239

COC(OC)[C@@H]1CCCN1C(=O)[C@H]1NCC(=S)C1C(=O)C[C@H]1CCc2ccccc2C1

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PREP P48147 17/20 0.42
UGCG Q16739 1/20 0.39
ADRA1D P25100 1/20 0.36
ADRA1A P35348 1/20 0.36
ADRA1B P35368 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9175056 1.00 PREP (0.42) PREPUGCGADRA1DADRA1AADRA1B
SCHEMBL9050343 0.96 PREP (0.44) PREPUGCG
SCHEMBL9049530 0.92 PREP (0.41) PREPUGCGADRA1DADRA1AADRA1B
SCHEMBL9048636 0.92 PREP (0.41) PREPUGCGADRA1DADRA1AADRA1B
SCHEMBL9051862 0.92 PREP (0.41) PREPUGCGADRA1DADRA1AADRA1B
SCHEMBL9050728 0.89 PREP (0.42) PREPUGCG
SCHEMBL9048329 0.87 PREP (0.39) PREPUGCG
SCHEMBL9047036 0.87 PREP (0.44) PREPUGCGADRA1DADRA1AADRA1B
SCHEMBL9046571 0.87 PREP (0.44) PREPUGCGADRA1DADRA1AADRA1B
SCHEMBL9051167 0.85 PREP (0.42) PREPUGCG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5407950-A Brain disorders, senile dementia ZERIA PHARMACEUTICAL CO., LTD. (JP) 1995-04-18 US disclosed