Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9169123 | 1.00 | NR5A1 (0.51) | NR5A1MEN1NPC1ALDH1A1GAA | |
| SCHEMBL9169962 | 1.00 | NR5A1 (0.51) | NR5A1MEN1NPC1ALDH1A1GAA | |
| SCHEMBL9427094 | 0.91 | PTPN11 (0.45) | NR5A1NPC1GAAMAPTRAB9A | |
| SCHEMBL9427096 | 0.91 | PTPN11 (0.45) | NR5A1NPC1GAAMAPTRAB9A | |
| SCHEMBL9167557 | 0.91 | PTPN11 (0.45) | NR5A1NPC1GAAMAPTRAB9A | |
| SCHEMBL9426142 | 0.91 | PTPN11 (0.45) | NR5A1NPC1GAAMAPTRAB9A | |
| SCHEMBL9427282 | 0.91 | PTPN11 (0.45) | NR5A1NPC1GAAMAPTRAB9A | |
| SCHEMBL9426854 | 0.91 | PTPN11 (0.45) | NR5A1NPC1GAAMAPTRAB9A | |
| SCHEMBL9426763 | 0.91 | PTPN11 (0.45) | NR5A1NPC1GAAMAPTRAB9A | |
| SCHEMBL9426374 | 0.91 | PTPN11 (0.45) | NR5A1NPC1GAAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428665-B1 | FLUOROPHENYL PYRIMIDINES | MERCK PATENT GMBH (DE) | 1995-04-05 | — | — | EP | disclosed |
| US-5340497-A | Ferroelectric liquid crystal | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-08-23 | — | — | US | disclosed |
| EP-0428665-A1 | FLUOROPHENYL PYRIMIDINES. | MERCK PATENT GMBH (DE) | 1991-05-29 | — | — | EP | disclosed |
| WO-1990015116-A1 | FLUOROPHENYL PYRIMIDINES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-12-13 | — | — | WO | disclosed |