SCHEMBL917115

SCHEMBL917115

BrCc1ccon1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27979122 0.80
SCHEMBL292468 0.74
SCHEMBL851507 0.74
SCHEMBL7005125 0.74
SCHEMBL8113516 0.74
SCHEMBL1752359 0.74
SCHEMBL541847 0.74
SCHEMBL11612891 0.74
SCHEMBL535894 0.74
SCHEMBL19135559 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105801509-B The preparation method and purposes of a kind of chalcone derivative 中国科学院新疆理化技术研究所 2018-01-05 CN claimed
CN-105801509-A Preparation method and application of phenylisoxazole-containing chalcone derivatives 中国科学院新疆理化技术研究所 2016-07-27 CN claimed
EP-3684773-B1 THAILANSTATIN ANALOGS PH PHARMA CO LTD (KR) 2026-04-29 EP disclosed
US-20260008758-A1 LINEAR DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF INSMED INCORPORATED 2026-01-08 US disclosed
WO-2025202922-A1 IMIDAZOPYRIDAZINE IL-17 INHIBITOR COMPOUNDS JANSSEN PHARMACEUTICA NV (BE) 2025-10-02 WO disclosed
US-20240360082-A1 SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS NOVARTIS AG (CH) 2024-10-31 US disclosed
EP-4373809-A1 SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS Novartis AG (CH) 2024-05-29 EP disclosed
CN-117980292-A Substituted pyridone compounds for the treatment of orthomyxoviral infections 诺华股份有限公司 2024-05-03 CN disclosed
CN-110869352-B Chemical compound 诺瑟拉有限公司 2023-11-28 CN disclosed
CN-111788208-B Talarstatin analogues PH制药有限公司 2023-11-24 CN disclosed
US-11691982-B2 Thailanstatin analogs PH PHARMA CO., LTD. (KR) 2023-07-04 US disclosed
WO-2005084315-A2 PYRANOINDOLE DERIVATIVES AND THE USE THEREOF FOR THE TREATMENT OF HEPATITIS C VIRUS INFECTION OR DISEASE VIROPHARMA INCORPORATED (US) 2005-09-15 WO disclosed
US-6855843-B2 Inhibitors of α4 mediated cell adhesion TANABE SEIYAKU CO., LTD. (JP) 2005-02-15 US disclosed
US-20030191118-A1 Inhibitors of alpha4 mediated cell adhesion TANABE SEIYAKU CO., LTD. 2003-10-09 US disclosed
US-6521666-B1 Inhibitors of α4 mediated cell adhesion TANABE SEIYAKU CO., LTD. (JP) 2003-02-18 US disclosed
US-20030032642-A1 Thiazolopyrimidines and thier use as modulators of chemokine receptor activity ASTRAZENECA AB (SE) 2003-02-13 US disclosed
EP-1049662-A1 INHIBITORS OF ALPHA4 MEDIATED CELL ADHESION TANABE SEIYAKU CO., LTD. (JP) 2000-11-08 EP disclosed
WO-1999036393-A1 INHIBITORS OF α4 MEDIATED CELL ADHESION TANABE SEIYAKU CO., LTD. (JP) 1999-07-22 WO disclosed
US-4336059-A Herbicidal and plant-growth-regulating N-(heterocyclyl)-methylacetanilide CHEVRON RESEARCH COMPANY (US) 1982-06-22 US disclosed
US-4221584-A Herbicidal and plant-growth-regulating N-(heterocyclyl)-methylacetanilides CHEVRON RESEARCH COMPANY (US) 1980-09-09 US disclosed