Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.50 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14754950 | 0.91 | TSHR (0.60) | TSHRALDH1A1KDM4EMAPK1HIF1A | |
| SCHEMBL18062304 | 0.91 | TSHR (0.60) | TSHRALDH1A1KDM4EMAPK1HIF1A | |
| SCHEMBL451967 | 0.91 | TSHR (0.60) | TSHRALDH1A1KDM4EMAPK1HIF1A | |
| SCHEMBL636411 | 0.89 | TSHR (0.58) | TSHRALDH1A1KDM4EMAPK1HIF1A | |
| SCHEMBL13302779 | 0.89 | TSHR (0.58) | TSHRALDH1A1KDM4EMAPK1HIF1A | |
| SCHEMBL12107779 | 0.87 | — | — | |
| SCHEMBL16299187 | 0.85 | TSHR (0.54) | TSHRALDH1A1KDM4EMAPK1HIF1A | |
| SCHEMBL14752402 | 0.85 | TSHR (0.54) | TSHRALDH1A1KDM4EMAPK1HIF1A | |
| SCHEMBL10272259 | 0.85 | TSHR (0.54) | TSHRALDH1A1KDM4EMAPK1HIF1A | |
| SCHEMBL15444091 | 0.85 | TSHR (0.54) | TSHRALDH1A1KDM4EMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514282-B1 | Alkylamino mercaptoalkylamides or salts thereof acceptable for cosmetic use, their use as a reducing agent and a process for the permanent deformation of hair | OREAL (FR) | 1996-04-10 | — | — | EP | claimed |
| EP-0577473-B1 | Reducing cosmetic composition for the permanent deformation of hair based on a mercaptoalkylamino-amide and process for the permanent deformation of hair | OREAL (FR) | 1995-12-20 | — | — | EP | claimed |
| EP-0568695-B1 | COSMETIC COMPOSITION FOR HAIR PERMING CONTAINING CYSTEIN BROMHYDRATE AND/OR 2-MERCAPTO ETHYLAMINE BROMHYDRATE AS THE REDUCING AGENT | OREAL (FR) | 1995-09-06 | — | — | EP | claimed |
| US-5334377-A | Reduction of the disulfide bond of keratin; the oxidation | L'OREAL (FR) | 1994-08-02 | — | — | US | claimed |
| EP-0577473-A1 | Reducing cosmetic composition for the permanent deformation of hair based on a mercaptoalkylamino-amide and process for the permanent deformation of hair | L'OREAL (FR) | 1994-01-05 | — | — | EP | claimed |
| EP-0568695-A1 | COSMETIC COMPOSITION FOR HAIR PERMING CONTAINING CYSTEIN BROMHYDRATE AND/OR 2-MERCAPTO ETHYLAMINE BROMHYDRATE AS THE REDUCING AGENT. | OREAL (FR) | 1993-11-10 | — | — | EP | claimed |
| EP-0432000-B1 | REDUCING COMPOSITION FOR PERMANENT HAIRWAVING, COMPRISING AS REDUCING AGENT AN AMINO-MERCAPTOALKYLAMIDE OR ONE OF ITS SALTS, AND ITS USE IN A PROCESS FOR PERMANENT HAIRWAVING | L'OREAL (FR) | 1993-08-11 | — | — | EP | claimed |
| WO-1993010751-A1 | COSMETIC COMPOSITION FOR HAIR PERMING CONTAINING CYSTEIN BROMHYDRATE AND/OR 2-MERCAPTO ETHYLAMINE BROMHYDRATE AS THE REDUCING AGENT | L'OREAL (FR) | 1993-06-10 | — | — | WO | claimed |
| WO-1993001791-A1 | AZEOTROPIC BLEND OF PROPYL 2-HYDROXY THIOGLYCOLATE AND ETHYL 1-METHYL 2-HYDROXY THIOGLYCOLATE, PROCESS FOR ITS PREPARATION AND USE THEREOF IN A PROCESS FOR ACHIEVING A PERMANENT CHANGE IN HAIR WAVINESS | L'OREAL (FR) | 1993-02-04 | — | — | WO | claimed |
| EP-0514282-A1 | Alkylamino mercaptoalkylamides or salts thereof acceptable for cosmetic use, their use as a reducing agent and a process for the permanent deformation of hair | L'OREAL (FR) | 1992-11-19 | — | — | EP | claimed |
| US-5085860-A | Odorless | L'OREAL (FR) | 1992-02-04 | — | — | US | claimed |
| EP-0432000-A1 | Reducing composition for permanent hairwaving, comprising as reducing agent an amino-mercaptoalkylamide or one of its salts, and its use in a process for permanent hairwaving | L'OREAL (FR) | 1991-06-12 | — | — | EP | claimed |
| CN-112384505-B | Therapeutic heterocyclic compounds | 吉利德科学公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-111954675-B | 3' -Cyclic dinucleotides | 捷克共和国有机化学与生物化学研究所 | 2025-04-01 | — | — | CN | disclosed |
| CN-113574063-B | 3' -Cyclic dinucleotides and prodrugs thereof | 捷克共和国有机化学与生物化学研究所 | 2025-03-18 | — | — | CN | disclosed |
| CN-113543851-B | 2'3' -Cyclic dinucleotides and prodrugs thereof | 捷克共和国有机化学与生物化学研究所 | 2025-03-18 | — | — | CN | disclosed |
| WO-1993001791-A1 | AZEOTROPIC BLEND OF PROPYL 2-HYDROXY THIOGLYCOLATE AND ETHYL 1-METHYL 2-HYDROXY THIOGLYCOLATE, PROCESS FOR ITS PREPARATION AND USE THEREOF IN A PROCESS FOR ACHIEVING A PERMANENT CHANGE IN HAIR WAVINESS | L'OREAL (FR) | 1993-02-04 | — | — | WO | disclosed |
| EP-0514282-A1 | Alkylamino mercaptoalkylamides or salts thereof acceptable for cosmetic use, their use as a reducing agent and a process for the permanent deformation of hair | L'OREAL (FR) | 1992-11-19 | — | — | EP | disclosed |
| US-5085860-A | Odorless | L'OREAL (FR) | 1992-02-04 | — | — | US | disclosed |
| EP-0432000-A1 | Reducing composition for permanent hairwaving, comprising as reducing agent an amino-mercaptoalkylamide or one of its salts, and its use in a process for permanent hairwaving | L'OREAL (FR) | 1991-06-12 | — | — | EP | disclosed |