Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9327268 | 1.00 | TSHR (0.42) | TSHRTHRBFAAHTRPV1CYP1A2 | |
| SCHEMBL11146562 | 1.00 | TSHR (0.42) | TSHRTHRBFAAHTRPV1CYP1A2 | |
| SCHEMBL28148579 | 1.00 | TSHR (0.42) | TSHRTHRBFAAHTRPV1CYP1A2 | |
| SCHEMBL16909645 | 1.00 | TSHR (0.42) | TSHRTHRBFAAHTRPV1CYP1A2 | |
| SCHEMBL7147029 | 1.00 | TSHR (0.42) | TSHRTHRBFAAHTRPV1CYP1A2 | |
| SCHEMBL9785660 | 1.00 | TSHR (0.42) | TSHRTHRBFAAHTRPV1CYP1A2 | |
| SCHEMBL6859421 | 0.95 | TSHR (0.42) | TSHRTHRBFAAHTRPV1CYP1A2 | |
| SCHEMBL15552969 | 0.91 | TSHR (0.42) | TSHRTHRBFAAHTRPV1CYP1A2 | |
| SCHEMBL8976924 | 0.91 | TSHR (0.42) | TSHRTHRBFAAHTRPV1CYP1A2 | |
| SCHEMBL1859713 | 0.87 | TSHR (0.52) | TSHRFAAHCYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646155-A1 | SUBSTITUTED PYRIMIDINES AND SUBSTITUTED TRIAZINES AS RUBBER-TO-METAL ADHESION PROMOTERS | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1995-04-05 | — | — | EP | disclosed |