Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8136233 | 0.86 | CYP2D6 (0.66) | NR1I2CYP3A4CYP2D6NPC1RAB9A | |
| SCHEMBL8876100 | 0.82 | NPC1 (0.51) | NR1I2CYP3A4CYP2D6NPC1RAB9A | |
| SCHEMBL8875583 | 0.82 | NPC1 (0.56) | NR1I2CYP3A4CYP2D6NPC1RAB9A | |
| SCHEMBL8132503 | 0.82 | CYP3A4 (0.62) | NR1I2CYP3A4CYP2D6NPC1RAB9A | |
| SCHEMBL8874875 | 0.80 | NR1I2 (0.76) | NR1I2CYP3A4CYP2D6 | |
| SCHEMBL8132486 | 0.77 | CYP2D6 (0.51) | NR1I2CYP3A4CYP2D6NPC1RAB9A | |
| SCHEMBL8875601 | 0.76 | CYP2D6 (0.53) | NR1I2CYP3A4CYP2D6NPC1RAB9A | |
| SCHEMBL8128995 | 0.76 | CYP2D6 (0.53) | NR1I2CYP3A4CYP2D6NPC1RAB9A | |
| SCHEMBL8135362 | 0.76 | CYP2D6 (0.50) | NR1I2CYP3A4CYP2D6NPC1RAB9A | |
| SCHEMBL8135581 | 0.76 | CYP3A4 (0.52) | NR1I2CYP3A4CYP2D6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5464848-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1995-11-07 | — | — | US | disclosed |