Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.49 |
| ▸ | RELA | Q04206 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | ACR | P10323 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9181159 | 1.00 | NPC1 (0.49) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL10338744 | 0.91 | NPC1 (0.50) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9251197 | 0.87 | NPC1 (0.60) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9640112 | 0.87 | NPC1 (0.60) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9640882 | 0.87 | NPC1 (0.60) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9641048 | 0.87 | NPC1 (0.60) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9641364 | 0.87 | NPC1 (0.60) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9641092 | 0.87 | NPC1 (0.60) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9641065 | 0.87 | NPC1 (0.60) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9640196 | 0.87 | NPC1 (0.60) | NPC1LMNANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992001766-A1 | FERROELECTRIC LIQUID CRYSTAL COMPOSITIONS CONTAINING HALOGENATED CORES AND CHIRAL HALOALKOXY TAIL UNITS | DISPLAYTECH, INC. (US) | 1992-02-06 | — | — | WO | claimed |
| US-5422037-A | For electro-optical and display devices | DISPLAYTECH, INC. (US) | 1995-06-06 | — | — | US | disclosed |
| US-5180520-A | Ferroelectric liquid crystal compositions containing halogenated cores and chiral halogenated cores and chiral haloalkoxy tail units | UNIVERSITY RESEARCH CORPORATION (US) | 1993-01-19 | — | — | US | disclosed |
| WO-1992001766-A1 | FERROELECTRIC LIQUID CRYSTAL COMPOSITIONS CONTAINING HALOGENATED CORES AND CHIRAL HALOALKOXY TAIL UNITS | DISPLAYTECH, INC. (US) | 1992-02-06 | — | — | WO | disclosed |