Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9177642 | 1.00 | HDAC6 (0.33) | HDAC6NPSR1HDAC1HDAC2POLB | |
| SCHEMBL25165406 | 0.82 | HDAC6 (0.33) | HDAC6NPSR1HDAC1HDAC2 | |
| SCHEMBL23977802 | 0.81 | NPSR1 (0.33) | HDAC6NPSR1HDAC1HDAC2 | |
| SCHEMBL24490826 | 0.81 | NPSR1 (0.33) | HDAC6NPSR1HDAC1HDAC2 | |
| SCHEMBL30073859 | 0.81 | NPSR1 (0.33) | HDAC6NPSR1HDAC1HDAC2 | |
| SCHEMBL2837457 | 0.80 | HDAC6 (0.35) | HDAC6HDAC1HDAC2 | |
| SCHEMBL23193949 | 0.79 | NPSR1 (0.33) | HDAC6NPSR1HDAC1HDAC2 | |
| SCHEMBL1028060 | 0.77 | POLB (0.45) | HDAC6HDAC1HDAC2POLB | |
| SCHEMBL9063966 | 0.75 | HDAC6 (0.42) | HDAC6HDAC1HDAC2 | |
| SCHEMBL25165313 | 0.75 | HDAC6 (0.33) | HDAC6NPSR1HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0652864-A1 | HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-05-17 | — | — | EP | disclosed |
| WO-1994002448-A1 | HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-02-03 | — | — | WO | disclosed |