Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1278399 | 0.98 | GAA (0.56) | GAAKMT2AVCAM1MAPTRXFP1 | |
| SCHEMBL28432360 | 0.97 | GAA (0.55) | GAAKMT2AVCAM1MAPTRXFP1 | |
| SCHEMBL39476 | 0.97 | GAA (0.55) | GAAKMT2AVCAM1MAPTRXFP1 | |
| SCHEMBL11739838 | 0.97 | GAA (0.55) | GAAKMT2AVCAM1MAPTRXFP1 | |
| SCHEMBL11725011 | 0.97 | GAA (0.55) | GAAKMT2AVCAM1MAPTRXFP1 | |
| SCHEMBL1278250 | 0.93 | GAA (0.58) | GAAKMT2AVCAM1MAPTMEN1 | |
| Methane SCHEMBL4595782 | 0.92 | GAA (0.56) | GAAKMT2AVCAM1MAPTMEN1 | |
| Methane SCHEMBL19206302 | 0.92 | GAA (0.56) | GAAKMT2AVCAM1MAPTMEN1 | |
| SCHEMBL2399238 | 0.88 | GAA (0.47) | GAAKMT2AVCAM1MAPTRXFP1 | |
| SCHEMBL39190 | 0.86 | GAA (0.66) | GAAKMT2AVCAM1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426573-B1 | Phenoxypropylamine derivatives or salts thereof and antiulcer agents containing the same | TERUMO CORP (JP) | 1995-05-24 | — | — | EP | disclosed |
| US-5037837-A | 5-lipoxygenase inhibitor | TERUMO KABUSHIKI KAISHA (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0426573-A2 | Phenoxypropylamine derivatives or salts thereof and antiulcer agents containing the same | TERUMO KABUSHIKI KAISHA (JP) | 1991-05-08 | — | — | EP | disclosed |