⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL915571 | 0.91 | SSTR5 (0.33) | — | |
| SCHEMBL3828712 | 0.90 | — | — | |
| SCHEMBL916684 | 0.90 | SSTR5 (0.34) | — | |
| SCHEMBL917074 | 0.90 | FFAR1 (0.32) | — | |
| SCHEMBL917073 | 0.89 | GRIN1 (0.30) | — | |
| SCHEMBL916371 | 0.89 | MAP3K12 (0.31) | — | |
| SCHEMBL3547325 | 0.89 | GRM2 (0.32) | — | |
| SCHEMBL917566 | 0.88 | SCN10A (0.34) | — | |
| SCHEMBL12904306 | 0.87 | PDE4B (0.36) | — | |
| SCHEMBL4983896 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021473-A1 | INHIBITORS OF PHOSPHODIESTERASE TYPE-IV | RANBAXY LABORATORIES LIMITED | 2011-01-27 | — | — | US | claimed |
| EP-2086948-A2 | INHIBITORS OF PHOSPHODIESTERASE TYPE-IV | Ranbaxy Laboratories Limited (IN) | 2009-08-12 | — | — | EP | claimed |
| WO-2008035315-A9 | INHIBITORS OF PHOSPHODIESTERASE TYPE-IV | RANBAXY LAB LTD (IN) | 2008-10-23 | — | — | WO | claimed |
| WO-2008035315-A2 | INHIBITORS OF PHOSPHODIESTERASE TYPE-IV | RANBAXY LABORATORIES LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| US-20110021473-A1 | INHIBITORS OF PHOSPHODIESTERASE TYPE-IV | RANBAXY LABORATORIES LIMITED | 2011-01-27 | — | — | US | disclosed |