Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9177857 | 0.96 | CYP3A4 (0.42) | CYP3A4TDP1TSHRKDM4EGAA | |
| SCHEMBL16581500 | 0.87 | TSHR (0.39) | CYP3A4TDP1TSHRGAACNR2 | |
| SCHEMBL2850046 | 0.82 | CYP3A4 (0.41) | CYP3A4TDP1KDM4EGAADRD1 | |
| SCHEMBL4795718 | 0.79 | TDP1 (0.46) | CYP3A4TDP1TSHRKDM4EGAA | |
| SCHEMBL12774282 | 0.78 | TSHR (0.35) | CYP3A4TDP1TSHRCNR2AR | |
| SCHEMBL1622430 | 0.75 | TDP1 (0.46) | CYP3A4TDP1TSHRKDM4EGAA | |
| SCHEMBL2846078 | 0.75 | CYP3A4 (0.46) | CYP3A4TDP1KDM4EGAADRD1 | |
| SCHEMBL31718395 | 0.75 | TSHR (0.46) | CYP3A4TDP1TSHRGAACNR2 | |
| SCHEMBL6299189 | 0.75 | TSHR (0.46) | CYP3A4TDP1TSHRGAACNR2 | |
| SCHEMBL18287382 | 0.74 | CYP3A4 (0.41) | CYP3A4TDP1KDM4EGAADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479541-B1 | Iridium-optically active phosphine complex and catalytic production of optically active alcohols therewith | TAKASAGO PERFUMERY CO LTD (JP) | 1995-07-19 | — | — | EP | disclosed |
| US-5210332-A | Iridium-optically active phosphine complex and process for producing optically active alcohols using the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1993-05-11 | — | — | US | disclosed |
| US-5159093-A | IRIDIUM-OPTICALLY ACTIVE PHOSPHINE COMPLEX AND PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOLS USING THE SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1992-10-27 | — | — | US | disclosed |
| EP-0479541-A1 | Iridium-optically active phosphine complex and catalytic production of optically active alcohols therewith | Takasago International Corporation (JP) | 1992-04-08 | — | — | EP | disclosed |