Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.58 |
| ▸ | PNMT | P11086 | 2/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | DBH | P09172 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL622229 | 0.79 | IDO1 (0.58) | IDO1PNMTTAAR1SIGMAR1POLB | |
| Bromide SCHEMBL1964769 | 0.79 | IDO1 (0.58) | IDO1PNMTTAAR1SIGMAR1POLB | |
| SCHEMBL3298586 | 0.78 | IDO1 (0.64) | IDO1PNMTTAAR1SIGMAR1POLB | |
| SCHEMBL9177314 | 0.77 | IGF1R (0.58) | IDO1PNMTTAAR1SIGMAR1IGF1R | |
| SCHEMBL29494831 | 0.76 | IDO1 (0.61) | IDO1PNMTTAAR1SIGMAR1POLB | |
| SCHEMBL17372921 | 0.76 | IDO1 (0.61) | IDO1PNMTTAAR1SIGMAR1POLB | |
| SCHEMBL407334 | 0.76 | IDO1 (0.61) | IDO1PNMTTAAR1SIGMAR1POLB | |
| SCHEMBL16618385 | 0.74 | IDO1 (0.58) | IDO1PNMTTAAR1SIGMAR1POLB | |
| SCHEMBL231954 | 0.74 | IDO1 (0.58) | IDO1PNMTTAAR1SIGMAR1POLB | |
| Ammonia Solution, Strong SCHEMBL14485188 | 0.74 | IDO1 (0.58) | IDO1PNMTTAAR1SIGMAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5422360-A | Hydrazonoimidazolidin-4-one derivatives; treatment of diabetes and aging disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-06 | — | — | US | disclosed |
| EP-0531812-A1 | Maillard reaction inhibitor, process for producing it, composition containing it and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |