Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 2/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9179022 | 1.00 | MAPT (0.48) | MAPTTGM2HTTSYKKLK7 | |
| SCHEMBL26374272 | 0.88 | SMN1; SMN2 (0.50) | MAPTTGM2HTTSYKKLK7 | |
| SCHEMBL16573491 | 0.86 | MAPT (0.58) | MAPTTGM2HTTSYKKLK7 | |
| SCHEMBL17923247 | 0.86 | MAPT (0.58) | MAPTTGM2HTTSYKKLK7 | |
| SCHEMBL13243337 | 0.84 | HTT (0.44) | MAPTTGM2HTTSYKKLK7 | |
| SCHEMBL28633511 | 0.83 | MAPT (0.52) | MAPTTGM2HTTSYKKLK7 | |
| SCHEMBL5554812 | 0.83 | HTT (0.56) | MAPTTGM2HTTSYKKLK7 | |
| SCHEMBL5554967 | 0.83 | HTT (0.56) | MAPTTGM2HTTSYKKLK7 | |
| SCHEMBL18854869 | 0.83 | KLK7 (0.54) | MAPTKLK7KLK5 | |
| SCHEMBL18854887 | 0.83 | KLK7 (0.54) | MAPTKLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5476870-A | Immunosuppressants | FOURNIER INDUSTRIE ET SANTE (FR) | 1995-12-19 | — | — | US | disclosed |