Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 4/20 | 0.57 |
| ▸ | RARB | P10826 | 1/20 | 0.52 |
| ▸ | RARG | P13631 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.49 |
| ▸ | RXRA | P19793 | 3/20 | 0.47 |
| ▸ | RXRB | P28702 | 3/20 | 0.47 |
| ▸ | RXRG | P48443 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4861421 | 0.88 | SRD5A2 (0.57) | SRD5A2RARBRARGTP53TSHR | |
| SCHEMBL4859943 | 0.84 | SRD5A2 (0.53) | SRD5A2RARBRARGTP53TSHR | |
| SCHEMBL3241556 | 0.83 | SRD5A2 (0.61) | SRD5A2RARBRARGTP53TSHR | |
| SCHEMBL30144875 | 0.83 | SRD5A2 (0.61) | SRD5A2RARBRARGTP53TSHR | |
| SCHEMBL16429445 | 0.83 | SRD5A2 (0.61) | SRD5A2RARBRARGTP53TSHR | |
| SCHEMBL4131036 | 0.83 | SRD5A2 (0.61) | SRD5A2RARBRARGTP53TSHR | |
| SCHEMBL107327 | 0.83 | SRD5A2 (0.61) | SRD5A2RARBRARGTP53TSHR | |
| SCHEMBL9183366 | 0.82 | EPHX2 (0.46) | TSHREPHX2NR1H4ALDH1A1TDP1 | |
| SCHEMBL30144881 | 0.81 | SRD5A2 (0.59) | SRD5A2RARBRARGTP53TSHR | |
| Hydrochloric Acid SCHEMBL11564114 | 0.81 | SRD5A2 (0.59) | SRD5A2RARBRARGTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378728-A | Benzoic acid derivatives as antidiabetic agents | SANDOZ LTD. (CH) | 1995-01-03 | — | — | US | claimed |
| US-5378728-A | Benzoic acid derivatives as antidiabetic agents | SANDOZ LTD. (CH) | 1995-01-03 | — | — | US | disclosed |