Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9178787 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1TP53RAB9AMEN1 | |
| SCHEMBL9180559 | 0.88 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1TP53RAB9AMEN1 | |
| SCHEMBL10866376 | 0.86 | TSHR (0.46) | SMN1; SMN2TP53RAB9AMEN1KMT2A | |
| SCHEMBL11691410 | 0.84 | KMT2A (0.61) | SMN1; SMN2NPC1TP53RAB9AMEN1 | |
| SCHEMBL11691407 | 0.84 | KMT2A (0.61) | SMN1; SMN2NPC1TP53RAB9AMEN1 | |
| SCHEMBL2823929 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1TP53RAB9AMEN1 | |
| SCHEMBL2823927 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1TP53RAB9AMEN1 | |
| SCHEMBL11507860 | 0.83 | CYP2D6 (0.56) | SMN1; SMN2NPC1TP53RAB9AMEN1 | |
| SCHEMBL11511887 | 0.81 | MEN1 (0.57) | SMN1; SMN2NPC1TP53RAB9AMEN1 | |
| SCHEMBL3060705 | 0.81 | MAPT (0.51) | SMN1; SMN2NPC1TP53RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371253-B1 | Method and reagents for detecting amphetamine and/or d-methamphetamine in biological samples | ABBOTT LAB (US) | 1995-09-13 | — | — | EP | disclosed |
| US-5262333-A | Fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1993-11-16 | — | — | US | disclosed |
| EP-0371253-A2 | Method and reagents for detecting amphetamine and/or d-methamphetamine in biological samples | ABBOTT LABORATORIES (US) | 1990-06-06 | — | — | EP | disclosed |