SCHEMBL9179076

SCHEMBL9179076

CC=CC(=O)OCCC[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.40
HCAR2 Q8TDS4 4/20 0.36
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TSHR P16473 2/20 0.31
HPGD P15428 1/20 0.31
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9763742 0.98 ATM (0.41) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL1632990 0.91 ATM (0.44) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL8640131 0.91 ATM (0.44) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL64811 0.89 ATM (0.46) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL8356269 0.89 ATM (0.36) ATMHCAR2
SCHEMBL8050990 0.89 ATM (0.36) ATMHCAR2
SCHEMBL9301205 0.86 ATM (0.43) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL10839217 0.86 ATM (0.43) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL10769687 0.85 HCAR2 (0.54) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9764023 0.85 ATM (0.40) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0250093-B1 Polysiloxane-grafted copolymer pressure sensitive adhesive composition and sheet materials coated therewith MINNESOTA MINING & MFG (US) 1995-07-19 EP disclosed
EP-0210041-B1 POLYSILOXANE-GRAFTED COPOLYMER RELEASE COATING ON SHEET MATERIALS AND ADHESIVE TAPES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-03-11 EP disclosed
US-4728571-A Polysiloxane-grafted copolymer release coating sheets and adhesive tapes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-03-01 US disclosed
EP-0250093-A2 Polysiloxane-grafted copolymer pressure sensitive adhesive composition and sheet materials coated therewith MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-12-23 EP disclosed
US-4693935-A LOW INITIAL PEEL ADHESION, POSITIONABLE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-09-15 US disclosed
EP-0210041-A2 Polysiloxane-grafted copolymer release coating on sheet materials and adhesive tapes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-01-28 EP disclosed