Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9183673 | 1.00 | GSR (0.45) | GSRALDH1A1GAATDP1CA2 | |
| SCHEMBL9181112 | 0.98 | GSR (0.46) | GSRALDH1A1GAATDP1CA2 | |
| SCHEMBL9177808 | 0.97 | GSR (0.47) | GSRALDH1A1GAATDP1CA2 | |
| SCHEMBL9179960 | 0.97 | GSR (0.47) | GSRALDH1A1GAATDP1CA2 | |
| SCHEMBL31438700 | 0.93 | GAA (0.50) | GSRALDH1A1GAATDP1CA2 | |
| SCHEMBL28339351 | 0.87 | GAA (0.45) | GSRALDH1A1GAATDP1CA2 | |
| SCHEMBL10621223 | 0.85 | GAA (0.46) | GSRALDH1A1GAATDP1CA2 | |
| SCHEMBL9179281 | 0.81 | GAA (0.46) | GSRALDH1A1GAATDP1CA2 | |
| SCHEMBL9183790 | 0.80 | GSR (0.71) | GSRALDH1A1GAACA2CA1 | |
| SCHEMBL9180095 | 0.80 | GSR (0.71) | GSRALDH1A1GAACA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0495450-B1 | Polyamine phenols as radioprotective agents | MERRELL DOW PHARMA (US) | 1995-07-26 | — | — | EP | claimed |
| US-5354782-A | Polyamine phenols as radioprotective agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-10-11 | — | — | US | claimed |
| EP-0495450-A2 | Polyamine phenols as radioprotective agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-22 | — | — | EP | claimed |
| EP-0495450-B1 | Polyamine phenols as radioprotective agents | MERRELL DOW PHARMA (US) | 1995-07-26 | — | — | EP | disclosed |
| US-5354782-A | Polyamine phenols as radioprotective agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-10-11 | — | — | US | disclosed |
| EP-0495450-A2 | Polyamine phenols as radioprotective agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-22 | — | — | EP | disclosed |