⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37918 | 0.50 | — | — | |
| SCHEMBL10545264 | 0.36 | — | — | |
| SCHEMBL2326 | 0.35 | — | — | |
| SCHEMBL34570 | 0.35 | — | — | |
| SCHEMBL25407819 | 0.32 | — | — | |
| SCHEMBL17688346 | 0.32 | — | — | |
| SCHEMBL17688348 | 0.32 | — | — | |
| SCHEMBL24013 | 0.32 | — | — | |
| Bromide SCHEMBL8858703 | 0.32 | — | — | |
| SCHEMBL17688345 | 0.32 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4276095-A2 | PROCESSES FOR PREPARING ASK1 INHIBITORS | Gilead Sciences, Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| EP-3693366-B1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | GILEAD SCIENCES INC (US) | 2023-06-28 | — | — | EP | disclosed |
| US-20220135527-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | GILEAD SCIENCES, INC. | 2022-05-05 | — | — | US | disclosed |
| US-11261161-B2 | Processes for preparing ASK1 inhibitors | GILEAD SCIENCES, INC. (US) | 2022-03-01 | — | — | US | disclosed |
| EP-3237404-B1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | GILEAD SCIENCES INC (US) | 2020-11-11 | — | — | EP | disclosed |
| US-20200283393-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | GILEAD SCIENCES, INC. | 2020-09-10 | — | — | US | disclosed |
| EP-3693366-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | Gilead Sciences, Inc. (US) | 2020-08-12 | — | — | EP | disclosed |
| US-10604490-B2 | Processes for preparing ASK1 inhibitors | GILEAD SCIENCES, INC. (US) | 2020-03-31 | — | — | US | disclosed |
| US-20180022708-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | GILEAD SCIENCES, INC. | 2018-01-25 | — | — | US | disclosed |
| US-9771328-B2 | Processes for preparing ASK1 inhibitors | GILEAD SCIENCES, INC. (US) | 2017-09-26 | — | — | US | disclosed |
| US-20170233350-A1 | PROCESSES FOR PREPARING ASK1 INHIBITORS | GILEAD SCIENCES, INC. | 2017-08-17 | — | — | US | disclosed |
| US-9586933-B2 | Processes for preparing ASK1 inhibitors | GILEAD SCIENCES, INC. (US) | 2017-03-07 | — | — | US | disclosed |
| US-20160244430-A1 | Processes for preparing ASK1 inhibitors | GILEAD SCIENCES, INC. (US) | 2016-08-25 | — | — | US | disclosed |
| US-20110003878-A1 | NOVEL DERIVATIVES OF PHTHALIMIDE AS HISTONE DEACETYLASE INHIBITORS | UNIVERSIDAD DE GRANADA (ES) | 2011-01-06 | — | — | US | disclosed |
| EP-2045239-A1 | NOVEL DERIVATIVES OF PHTHALIMIDE AS HISTONE DEACETYLASE INHIBITORS | Universidad De Granada (ES) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008003801-A1 | NOVEL DERIVATIVES OF PHTHALIMIDE AS HISTONE DEACETYLASE INHIBITORS | UNIVERSIDAD DE GRANADA (ES) | 2008-01-10 | — | — | WO | disclosed |