Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.55 |
| ▸ | RRM1 | P23921 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 4/20 | 0.40 |
| ▸ | FNTB | P49356 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536837 | 0.84 | ABCB1 (0.52) | ABCB1RRM1MAPTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8534947 | 0.83 | ABCB1 (0.53) | ABCB1RRM1MAPTKDM4EALDH1A1 | |
| SCHEMBL8644069 | 0.82 | ABCB1 (0.76) | ABCB1RRM1MAPTKDM4EALDH1A1 | |
| SCHEMBL8299655 | 0.82 | ABCB1 (0.76) | ABCB1RRM1MAPTKDM4EALDH1A1 | |
| SCHEMBL29640402 | 0.82 | ABCB1 (0.76) | ABCB1RRM1MAPTKDM4EALDH1A1 | |
| SCHEMBL8435621 | 0.82 | ABCB1 (0.76) | ABCB1RRM1MAPTKDM4EALDH1A1 | |
| SCHEMBL9187068 | 0.81 | ABCB1 (0.53) | ABCB1RRM1FNTAFNTB | |
| SCHEMBL9187135 | 0.80 | ABCB1 (0.51) | ABCB1RRM1FNTAFNTBALDH1A1 | |
| SCHEMBL9186633 | 0.79 | ABCB1 (0.71) | ABCB1RRM1MAPTKDM4EALDH1A1 | |
| SCHEMBL9181122 | 0.79 | ABCB1 (0.49) | ABCB1MAPTKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405843-A | Anticancer drug potentiators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-04-11 | — | — | US | disclosed |
| EP-0363212-B1 | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | MITSUI TOATSU CHEMICALS (JP) | 1995-01-04 | — | — | EP | disclosed |
| US-5204348-A | Quinoline derivatives | MITSUI TOATSU CHEMICALS INC. (JP) | 1993-04-20 | — | — | US | disclosed |
| US-5112817-A | Anticancer Drug Potentiators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0363212-A2 | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-04-11 | — | — | EP | disclosed |