Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 6/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10471320 | 0.91 | MAPK1 (0.58) | MAPK1SMN1; SMN2HTR2AKDM1ACHRM2 | |
| SCHEMBL2151191 | 0.89 | MAPK1 (0.77) | MAPK1SMN1; SMN2HTR2AKDM1ACHRM2 | |
| SCHEMBL11401106 | 0.82 | MAPK1 (0.42) | MAPK1SMN1; SMN2HTR2CLMNA | |
| SCHEMBL10471187 | 0.82 | MAPK1 (0.44) | MAPK1SMN1; SMN2KDM1AL3MBTL1LMNA | |
| SCHEMBL9186595 | 0.79 | MAPK1 (0.41) | MAPK1SMN1; SMN2HTR2CL3MBTL1LMNA | |
| SCHEMBL6970399 | 0.76 | MAPK1 (0.59) | MAPK1SMN1; SMN2HTR2AKDM1ACHRM2 | |
| SCHEMBL16938077 | 0.76 | MAPK1 (0.63) | MAPK1SMN1; SMN2CHRM2CHRM4CHRM5 | |
| Acetic Acid SCHEMBL10473378 | 0.75 | MAPK1 (0.42) | MAPK1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL14430492 | 0.75 | MAPK1 (0.44) | MAPK1SMN1; SMN2HTR2AKDM1A | |
| SCHEMBL21801631 | 0.75 | MAPK1 (0.53) | MAPK1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405843-A | Anticancer drug potentiators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-04-11 | — | — | US | disclosed |
| EP-0363212-B1 | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | MITSUI TOATSU CHEMICALS (JP) | 1995-01-04 | — | — | EP | disclosed |
| US-5204348-A | Quinoline derivatives | MITSUI TOATSU CHEMICALS INC. (JP) | 1993-04-20 | — | — | US | disclosed |
| US-5112817-A | Anticancer Drug Potentiators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0363212-A2 | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-04-11 | — | — | EP | disclosed |
| US-4912222-A | Antihistamines related to cyproheptadine | FISONS CORPORATION (US) | 1990-03-27 | — | — | US | disclosed |
| WO-1989012443-A1 | NOVEL DIBENZO-CYCLOHEPTENYL, -CYCLOHEPTYL AND -OXEPINYL AMINES HAVING ANTIHISTAMINIC PROPERTIES | FISONS CORPORATION (US) | 1989-12-28 | — | — | WO | disclosed |